Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required) is offered by National Institutes of Health. Max award: Not specified. Applications close on Nov 19, 2026.
| Opportunity number | PAR-25-226 |
|---|---|
| Agency | National Institutes of Health |
| Status | Posted |
| Posted | Nov 22, 2024 |
| Closes | Nov 19, 2026 |
| Award ceiling | Not specified |
| Award floor | Not specified |
| Total program funding | Not specified |
| Expected awards | Not specified |
| Who can apply | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Special district governments, Private institutions of higher education, County governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public housing authorities/Indian housing authorities, Small businesses, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), City or township governments, State governments, Independent school districts |
| Category | Health |
Summary (excerpt)
The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for phase 1 clinical trials with phase 1b/phase 2a clinical trials to streamline the early-stage evaluation of promising pharmacological interventions for Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD). Candidate interventions evaluated through this program, which can include small molecules or biologics …
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Before you apply
- Register your organization in SAM.gov and get a UEI — it can take weeks
- Create a Grants.gov account and check eligibility in the full notice (NOFO)
- Start early; the system gets busy near deadlines
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