Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed) is offered by National Institutes of Health. Max award: Not specified. Applications close on Jul 2, 2027.
| Opportunity number | RFA-TR-25-002 |
|---|---|
| Agency | National Institutes of Health |
| Status | Posted |
| Posted | Dec 6, 2024 |
| Closes | Jul 2, 2027 |
| Award ceiling | Not specified |
| Award floor | Not specified |
| Total program funding | Not specified |
| Expected awards | Not specified |
| Who can apply | Others (see text field entitled "Additional Information on Eligibility" for clarification), Special district governments, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal governments (Federally recognized), Public and State controlled institutions of higher education, Small businesses, Private institutions of higher education, State governments, Independent school districts, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, City or township governments, County governments |
| Category | Health |
Summary (excerpt)
This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical model to demonstrate that a proposed therapeutic agent warrants further development. In addition to preclinical efficacy, accompanying pharmacodynamic and pharmacokinetic studies would be supported. Therapeutic agents include small molecules, biologics or biotechnology-derived products. The goal of this NOFO is to spur…
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Before you apply
- Register your organization in SAM.gov and get a UEI — it can take weeks
- Create a Grants.gov account and check eligibility in the full notice (NOFO)
- Start early; the system gets busy near deadlines
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