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Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed)

Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed) is offered by National Institutes of Health. Max award: $2,000,000. Applications close on Dec 14, 2026.

Opportunity numberRFA-HG-27-007
AgencyNational Institutes of Health
StatusPosted
PostedOct 9, 2026
ClosesDec 14, 2026
Award ceiling$2,000,000
Award floorNot specified
Total program funding$15,000,000
Expected awards5
Who can applyPublic and State controlled institutions of higher education, County governments, Special district governments, City or township governments, For profit organizations other than small businesses, Public housing authorities/Indian housing authorities, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Native American tribal governments (Federally recognized), Small businesses, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Independent school districts, State governments, Native American tribal organizations (other than Federally recognized tribal governments), Others (see text field entitled "Additional Information on Eligibility" for clarification)
CategoryHealth

Summary (excerpt)

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to characterize genomic variation to assess the impact of individual variants on genome function. This will be accomplished by systematically perturbing variants or elements using one or more high-throughput methods; collecting data on the effects of variants in DNA, RNA, or protein-coding elements on molecular, cellular, or organismal phenotypes; and developing r…

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