HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) is offered by National Institutes of Health. Max award: Not specified. Applications close on Feb 20, 2029.
| Opportunity number | RFA-NS-27-007 |
|---|---|
| Agency | National Institutes of Health |
| Status | Posted |
| Posted | Jun 16, 2026 |
| Closes | Feb 20, 2029 |
| Award ceiling | Not specified |
| Award floor | Not specified |
| Total program funding | $11,000,000 |
| Expected awards | 3 |
| Who can apply | For profit organizations other than small businesses, Private institutions of higher education, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, State governments, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, City or township governments, Special district governments, County governments, Native American tribal governments (Federally recognized), Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Independent school districts |
| Category | Health |
Summary (excerpt)
The purpose of this Notice of Funding Opportunity (NOFO) is to support the preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics for the treatment of pain. The goal of the program is to accelerate the advancement of promising early-stage therapeutic candidates and facilitate their readiness for Phase II clinical trials. Applicants must have a promising small molecule or biologic le…
View the official listing and apply on Grants.gov
Before you apply
- Register your organization in SAM.gov and get a UEI — it can take weeks
- Create a Grants.gov account and check eligibility in the full notice (NOFO)
- Start early; the system gets busy near deadlines
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