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HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required) is offered by National Institutes of Health. Max award: Not specified. Applications close on Oct 30, 2026.

Opportunity numberPAR-27-045
AgencyNational Institutes of Health
StatusPosted
PostedSep 28, 2026
ClosesOct 30, 2026
Award ceilingNot specified
Award floorNot specified
Total program fundingNot specified
Expected awardsNot specified
Who can applyNonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, City or township governments, State governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Public and State controlled institutions of higher education, Independent school districts, Special district governments, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public housing authorities/Indian housing authorities, For profit organizations other than small businesses, County governments, Small businesses
CategoryHealth

Summary (excerpt)

The NIH Helping to End Addiction Long-term ® (HEAL) Initiative is releasing this Notice of Funding Opportunity (NOFO) to support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The phased projects supported by this program (of up to five years total in duration) will first identify and validate multi-tissue mechanisms underlying joint pain, then test non-pharmacologic or multimo…

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