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Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)

Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed) is offered by National Institutes of Health. Max award: $2,725,311. This is a forecast; the deadline is not set yet.

Opportunity numberPAR-28-019
AgencyNational Institutes of Health
StatusForecasted
PostedMay 20, 2026
ClosesNot set
Award ceiling$2,725,311
Award floor$212,004
Total program fundingNot specified
Expected awards4
Who can applySpecial district governments, Public housing authorities/Indian housing authorities, State governments, City or township governments, County governments, Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education, Native American tribal organizations (other than Federally recognized tribal governments), Independent school districts, Native American tribal governments (Federally recognized), For profit organizations other than small businesses
CategoryHealth

Summary (excerpt)

This NOFO is issued during a period of accelerating development, validation, and adoption of human new approach methodologies (NAMs). Accordingly, it has two integrated priorities for NIH-funded HIV/AIDS research: (1) implementation of a NAMs-enabled stewardship framework, including optional HIV-relevant human in vitro testing support and pilot benchmarking activities, to reduce or replace specific pathogen free (SPF) in vivo model use where scie…

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